Parenting|

Hey Parents: Add This Needle-Free Treatment For Allergic Reactions To Your Back-To-School Checklist

Ask your doctor about neffy® (epinephrine nasal spray) today.

Written by Deanna Pai

For a lot of parents, the start of a new school year can feel like a relief — no more endless requests for ice pops and camp pickups. But if your child has a food allergy, it can be fraught at best and nerve-wracking at worst; you never know when your child will sit next to a friend with a PB&J or eat a handful of trail mix with nuts. That risk is the daily reality of parenting a child with a severe food allergy, and why epinephrine should be a part of your back-to-school planning every year — after all, food allergies don’t go on break.

Now for the good news: There is now a needle-free treatment option available — neffy, an epinephrine nasal spray used for emergency treatment of allergic reactions including anaphylaxis, in adults and children who weigh 33 lbs. or greater.

  • neffy is small, discreet and easy to carry with your child anywhere they go — including their backpack, sports bag, or lunchbox.
  • neffy delivers the same trusted epinephrine found in a needle-injector but in a nasal spray, making it potentially more appealing to children and needle-phobes alike.
  • neffy works as well as a needle-injector and is designed to be safe and easy to use at the first sign of symptoms. Even if you aren’t there, teachers, coaches, and others can quickly step in to help
  • The epinephrine in neffy is rapidly absorbed into the nasal passage to reverse the reaction and starts to work in under a minute. neffy may cause side effects, so it's important to talk to a doctor about any medical conditions or medications to determine if neffy is the right option.
  • Have a child with a constant cold? The nasal spray can still get through stuffy noses.

As you prepare for back to school and the never ending to-do list, make sure to schedule an appointment with your pediatrician or allergist before the avalanche of parent-teacher meetings and soccer games start. But to make life easier, you can also get neffy online; eligible patients can book a free virtual visit and pay as little as $0 with commercial insurance. Patients should not pay more than $199 for neffy.

neffy has a longer shelf life than epinephrine needle-injectors — between 2 years to 2.5 years, depending on the dose & from the date of manufacture — but all epinephrine does eventually expire, make sure to check to see if your epinephrine is up to date. Same goes if you’ve been storing yours in the garage or the trunk of your car; some epinephrine can’t be stored above or below certain temperatures, so you may need to restock if you’re not sure what your stash has been through. The good news is neffy can be accidentally exposed to high temperatures up to 122⁰F (50⁰C) and remains stable. Remember to store neffy at room temperature, between 68⁰F to 77⁰F (20⁰C to 25⁰C). Your child should have two neffy devices on them at all times. Make sure your child has a set of devices at the places they go most often — home, school, sports, grandparents house.

Next, make sure your child knows what to do if they experience an allergic reaction. Part of that is learning how to identify the signs of a serious allergic reaction, like the swelling of the tongue, shortness of breath, and full-body hives. But just as important is that they know how to use their epinephrine device. Since neffy doesn't have a needle, it’s designed to be easy to use. Your child might be less likely to hesitate since there isn’t a needle — which is especially important when it comes to allergic reactions, which can become more dangerous as the seconds tick by. In fact, needles are part of the reason that 83% of people hesitate to use epinephrine — or just don't use it at all. You can even get a neffy trainer so your child can practice.

Finally, talk to the school staff; check with the school nurses (who frequently have epinephrine on hand) as well as the educators and kitchen staff to make sure they know about your child’s allergy and what your plan is. They can make accommodations to keep your child as safe and risk-free as possible.

As much as you can prepare your child and those who care for them about the risk of a life-threatening allergic reaction, accidental allergen exposure can happen in the middle of the cafeteria or during an after-school hangout. That’s where early practice and prep can make all the difference. Whether you have a newly minted kindergartener with a tree nut allergy or a rising college sophomore who’s allergic to eggs, mapping out your allergy gameplan, to include a trusted epinephrine option like neffy, can help you — and your child stay prepared and— ace another school year. Talk to your doctor about neffy today or visit neffy.com to learn more.

Please keep scrolling to view neffy’s Important safety information.

WHAT IS neffy?

neffy is a nasal spray used for emergency treatment of allergic reactions including anaphylaxis, in adults and children who weigh 33 lbs or greater.

IMPORTANT SAFETY INFORMATION

What is the most important information that I should know about neffy?

neffy contains epinephrine, a medicine used to treat allergic emergencies (anaphylaxis). Anaphylaxis can be life-threatening, can happen in minutes, and can be caused by stinging and biting insects, allergy injections, foods, medicines, exercise, or other unknown causes.

Always carry two neffy nasal sprays with you because you may not know when anaphylaxis may happen and because you may need a second dose of neffy if symptoms continue or come back. Each neffy contains a single dose of epinephrine. neffy is for use in the nose only.

Use neffy right away, as soon as you notice symptoms of an allergic reaction. If symptoms continue or get worse after the first dose of neffy, a second dose is needed. If needed, administer a second dose using a new neffy in the same nostril starting 5 minutes after the first dose. Get emergency medical help for further treatment of the allergic emergency (anaphylaxis), if needed after using neffy.

Tell your healthcare provider if you have underlying structural or anatomical nasal conditions, about all the medicines you take, and about all your medical conditions, especially if you have heart problems, kidney problems, low potassium in your blood, Parkinson's disease, thyroid problems, high blood pressure, diabetes, are pregnant or plan to become pregnant, or plan to breastfeed.

Tell your healthcare provider if you take or use other nasal sprays or water pills (diuretics) or if you take medicines to treat depression, abnormal heart beats, Parkinson's disease, heart disease, thyroid disease, medicines used in labor, and medicines to treat allergies. neffy and other medications may affect each other, causing side effects. neffy may affect the way other medicines work, and other medicines may affect how neffy works.

What are the side effects of neffy?

neffy may cause serious side effects. If you have certain medical conditions or take certain medicines, your condition may get worse, or you may have more or longer lasting side effects when you use neffy.

Common side effects of neffy include: nasal discomfort, headache, throat irritation, chest and nasal congestion, feeling overly excited, nervous or anxious, nose bleed, nose pain, sneezing, runny nose, dry nose or throat, tingling sensation, including in the nose, feeling tired, dizziness, nausea, and vomiting.

Tell your healthcare provider if you have any side effects that bother you or that do not go away after using neffy.

These are not all of the possible side effects of neffy. Call your healthcare provider for medical advice about side effects. To report side effects, contact ARS Pharmaceuticals Operations, Inc. at 1‑877‑MY‑NEFFY (877‑696‑3339) or the FDA at 1‑800‑FDA‑1088 or www.fda.gov/medwatch.

Please see the full Prescribing Information and Patient Information for neffy.

NEF-US-1091 I 07/2026