If You Can Answer This 'Grey's Anatomy' Trivia, You Deserve A Harper Avery (Stat!)

Some TV shows get canceled after one season. Some TV shows are gifted with a respectable five- or six-season run. And then there are TV shows like Grey’s Anatomy that have withstood the test of time and lasted far beyond what anyone could have imagined. In fact, the show’s success has led to it becoming the longest-running medical drama on primetime television (sorry, ER). And while rumors about when it will end continue to make the rounds, it’s currently in the midst of its 18th season. Yes, you heard me right, 18 seasons of Grey’s! If you’re nodding your head right now and thinking, I know, well, you’re probably a fan. But just how big of a fan are you? The series has nearly 400 episodes under its belt, equating to a ton of Grey’s Anatomy trivia.

While that seems like a lot of footage, the show may stretch into Season 19 and possibly even Season 20. It remains beloved by millions of fans worldwide — and with good reason. From steamy on-call room hookups to complicated surgeries, this show never fails to leave its viewers on the edge of their seats in some form or another. The characters are impossible not to root for, and the storylines continuously kick you right in the feels. (Seriously, just try watching this show without a box of tissues by your side, I dare you.)

With that said, it’s high time we test your knowledge of Meredith Grey and the rest of the Grey Sloan gang with a bit of Grey’s Anatomy trivia that’ll prove just how deep your dedication goes. These questions would also make a perfect activity to spice up moms’ night in, to read on that long-overdue girls’ road trip you’ve been meaning to take, or to share with your best friend (or partner since we all know they secretly love it, too) during commercial breaks when you watch the next episode.

So, sit back, relax, and scrub in on the array of questions below.

Grey’s Anatomy Trivia Questions and Answers

1. Who created Grey’s Anatomy? Shonda Rhimes
2. What is the show’s title a reference to? The famous anatomy book Gray’s Anatomy
3. What was the series originally going to be called? Complications
4. What was Derek Shepherd’s nickname? McDreamy
5. What was Mark Sloan’s nickname? McSteamy
6. What was Lexie Grey’s nickname? Little Grey
7. How was Lexie related to Meredith? Half-sister
8. Where did Meredith go to college? Dartmouth
9. Which role did Sandra Oh initially hope to audition for? Dr. Bailey
10. What do the residents call the doll with plastic organs? Anatomy Jane
11. What was the original name of the hospital where everyone works Seattle Grace
12. What hospital did they end up merging with? Mercy West
13. That merger resulted in the hospital being renamed what? Seattle Grace Mercy West
14. What is the hospital’s current name? Grey Sloan Memorial Hospital
15. What is the name of Callie Torres, Arizona Robbins, and Mark Sloan’s daughter? Sofia
16. Who died as a result of the plane crash that took place at the end of Season 8? Lexie Grey and Mark Sloan
17. In the first season, Derek tells Meredith his favorite color. What is it? Indigo
18. Who does Cristina accidentally stab with an epi-pen in Season 8? Alex
19. What endearing term do Meredith and Cristina use to call each other? “My person”
20. Which well-known actor played the leader of the bomb squad in Season 2? Kyle Chandler
21. What design does Derek’s favorite scrub cap have on it? Ferry boats
22. What was his character’s name? Dylan Young
23. What secret was Derek keeping from Meredith in Season 1? That he was married
24. Why did Derek move to Seattle? His wife cheated on him with his best friend.
25. What is Derek Shepherd’s specialty? Neurosurgery
26. How many times has Miranda Bailey been married? Twice
27. How did George O’Malley die at the end of Season 5? He was hit by a bus
28. What was Preston Burke’s specialty? Cardiothoracic surgery
29. What bar do the doctors like to go to after work? The Emerald City Bar (though it’s mainly referred to as Joe’s, the name of the bartender/owner)
30. Which character has a photographic memory? Lexie Grey
31. What is Addison Montgomery’s specialty? Neonatal surgery
32. Whose LVAD wire does Izzie Stevens cut in Season 2? Denny Duquette
33. How much money did Denny leave Izzie in his will? $8.7 million
34. What was Denny waiting for on the donor list? A new heart
35. Which well-known actor played Denny? Jeffrey Dean Morgan
36. What was the name of Meredith’s dog? Doc
37. Which well-known actor had a cameo as Meredith’s vet boyfriend? Chris O’Donnell
38. What was his character’s nickname? McVet
39. Who did George have a crush on at the start of the show? Meredith
40. What’s the significance of the sparkle pager in Season 4? Whichever resident has it gets the opportunity to take any surgery of their choosing from the other residents
41. What other profession has Izzie dabbled in? Modeling
42. What secret was Meredith keeping about her mother in Season 1? That she had Alzheimer’s
43. What STD does George contract in Season 1? Syphilis
44. How many kids do Derek and Meredith have? Three
45. In Season 6, which resident gets shot first during the hospital shooting? Reed
46. What are their names? Zola, Bailey, and Ellis
47. Where did George and Callie get married? Las Vegas
48. What is Derek’s middle name? Christopher
49. Which character went on to star in the spinoff series, Private Practice? Addison Montgomery
50. Out of the core five characters — Izzie, Cristina, Meredith, George, and Alex — who failed their intern exam? George
51. Who replaced Preston Burke as Chief of Cardio in Season 4? Dr. Erica Hahn
52. Who does Hahn share a romantic relationship with? Callie
53. What does Meredith’s former BFF, Sadie, call her as a nickname? Death
54. What does Meredith call Sadie? Die
55. What famous actor passed on the role of Derek Shepherd? Rob Lowe
56. What injury did Mark Sloan sustain while having sex with Lexie? A penile fracture
57. Which One Tree Hill stars made cameos on Grey’s? Jana Kramer, Joy Lez, and Hilarie Burton
58. What was George’s nickname? 007
59. Where did Ellen Pompeo and her character, Meredith, both grow up? Boston
60. Why does Andrew DeLuca get killed in Season 17? He uncovers a human trafficking ring
61. After Hahn leaves, who becomes the new Head of Cardio? Teddy Altman
62. In what other production did Patrick Dempsey and Kevin McKidd costar? Made of Honor (2008)
63. What specialty does Alex Karev end up choosing? Pediatrics
64. Who plays Teddy’s first husband, Henry, in Season 7? Scott Foley
65. What beauty mishap befalls Cristina on her wedding day in Season 3? A waxing accident that takes off her eyebrows
66. Why did they get married? So that Henry could use Teddy’s medical insurance
67. What is Jo Wilson’s real first name? Brooke
68. Who does April lose her virginity to? Jackson Avery
69. Who did Jessica Capshaw (Dr. Arizona Robbins) originally want to be her love interest? Justin Chambers (Dr. Alex Karev)
70. What’s the name of the nurse Derek Shepherd dates when he and Meredith are broken up? Rose
71. Which Grey’s character went on to star in the spinoff series, Station 19? Ben Warren
72. What stabs Cristina in Season 5 when she meets Owen Hunt? An icicle
73. What body part does Derek severely injure in the Season 8 plane crash? His hand
74. Where does Cristina temporarily move to after the events of the plane crash? Minnesota
75. What did Katherine Heigl cite as her reason for famously dropping out of Emmy consideration for her Grey’s role in 2008? A lack of material that would warrant a nomination
76. What is the name of Meredith’s dad? Thatcher
77. What did he die of in Season 15? Cancer
78. Which three actors starred in both Grey’s and Scream 3? Scott Foley, Neve Campbell, and Patrick Dempsey
79. What do Teddy and Owen name their daughter? Allison
80. What prestigious award does Cristina get nominated for in Season 10? Harper Avery
81. Does she win? No
82. At the end of Season 10, Cristina is offered the chance to run her very own research hospital in what country? Switzerland
83. Who made her this offer? Preston Burke
84. When Cristina leaves, what does she call Meredith (and not Derek)? The sun
85. Who are Maggie Pierce’s birth parents? Ellis Grey and Richard Webber
86. Why does Jo initially turn down Alex’s proposal? Because she’s already married
87. How does Derek Shepherd die? From severe brain injuries following a car accident
88. What is the name of Owen’s sister? Megan
89. How does Matthew propose to April? With a flashmob
90. Where do Arizona, Callie, and Sofia end up moving to? New York
91. Who was Amelia Shepherd’s mentor? Tom Koracick
92. Why does Alex ultimately leave Seattle and end his marriage to Jo? The revelation that Izzie secretly had his twins
93. What is Meredith’s speciality? General surgery
94. Who caught Callie dancing in her underwear when she was temporarily living in the hospital? Richard Webber
95. What are Grey’s Anatomy episodes named after? Song titles
96. Which music superstar has a cat named after Meredith Grey? Taylor Swift
97. How old was Maggie when she graduated from med school? 19
98. What season did the series stop using its opening theme sequence? Season 2
99. Who does Izzie hallucinate seeing as a result of her brain tumor? Denny
100. What was the song played in the original opening? “Cosy in the Rocket” by Psapp
101. Which OG character does not visit Meredith on the beach in Season 17? Cristina Yang